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Cellosaurus GSC-84 (CVCL_C6J0)

[Text version]
Cell line name GSC-84
Synonyms 84
Accession CVCL_C6J0
Resource Identification Initiative To cite this cell line use: GSC-84 (RRID:CVCL_C6J0)
Comments Group: Cancer stem cell line.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Brain, left temporal lobe; UBERON=UBERON_0002808.
Cell type: Neural stem cell; CL=CL_0000047.
Disease Oligodendroglioma (NCIt: C3288)
Oligodendroglioma (ORDO: Orphanet_251627)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=23650391; DOI=10.1073/pnas.1221478110; PMCID=PMC3666732
Mao P., Joshi K., Li J.-F., Kim S.-H., Li P.-P., Santana-Santos L., Luthra S., Chandran U.R., Benos P.V., Smith L., Wang M.-D., Hu B., Cheng S.-Y., Sobol R.W., Nakano I.
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
Proc. Natl. Acad. Sci. U.S.A. 110:8644-8649(2013)

PubMed=34934174; DOI=10.1038/s42003-021-02949-7; PMCID=PMC8692581
Li J.-F., Garavaglia S., Ye Z.-F., Moretti A., Belyaeva O.V., Beiser A., Ibrahim M., Wilk A., McClellan S., Klyuyeva A.V., Goggans K.R., Kedishvili N.Y., Salter E.A., Wierzbicki A., Migaud M.E., Mullett S.J., Yates N.A., Camacho C.J., Rizzi M., Sobol R.W.
A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells.
Commun. Biol. 4:1420.1-1420.16(2021)

Cross-references
Encyclopedic resources Wikidata; Q116049106
Gene expression databases GEO; GSM1638639
GEO; GSM1638640
GEO; GSM1638641
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3