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Cellosaurus LG2-MEL-220 (CVCL_C5VA)

[Text version]
Cell line name LG2-MEL-220
Synonyms LG-2-MEL-220
Accession CVCL_C5VA
Resource Identification Initiative To cite this cell line use: LG2-MEL-220 (RRID:CVCL_C5VA)
Comments Characteristics: Has lost the HLA-A*24, HLA-B*35 and HLA-C*4 alleles of the parent cell line (PubMed=12747754).
Doubling time: 38 hours (PubMed=12747754).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:16994; OS9; Simple; p.Pro446Leu (c.1337C>T); Zygosity=Homozygous (PubMed=12747754).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C5U8 (LG2-MEL)
Sex of cell Male
Age at sampling 31Y
Category Cancer cell line
Publications

PubMed=2967757; DOI=10.1002/eji.1830180503
Degiovanni G., Lahaye T., Herin M., Hainaut P., Boon T.
Antigenic heterogeneity of a human melanoma tumor detected by autologous CTL clones.
Eur. J. Immunol. 18:671-676(1988)

PubMed=12747754
Vigneron N., Ooms A., Morel S., Degiovanni G., van den Eynde B.J.
Identification of a new peptide recognized by autologous cytolytic T lymphocytes on a human melanoma.
Cancer Immun. 2:9-9(2002)

Cross-references
Encyclopedic resources Wikidata; Q116049689
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5