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Cellosaurus HEK293-SLC1A5 (CVCL_C5TT)

[Text version]
Cell line name HEK293-SLC1A5
Accession CVCL_C5TT
Resource Identification Initiative To cite this cell line use: HEK293-SLC1A5 (RRID:CVCL_C5TT)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:10943; SLC1A5.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=35834041; DOI=10.1007/s10637-022-01284-w
Duan Z.-L., Zhou Z.-Y., Lu F.-F., Zhang Y.-W., Guo X.-Q., Gui C.-S., Zhang H.-J.
Antitumor activity of mianserin (a tetracyclic antidepressant) primarily driven by the inhibition of SLC1A5-mediated glutamine transport.
Invest. New Drugs 40:977-989(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049303
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number6