Cellosaurus cell line CRICKi012-A (CVCL

Cross-references
Cell line name	CRICKi012-A
Synonyms	iFCI017
Accession	CVCL_C5T4
Resource Identification Initiative	To cite this cell line use: CRICKi012-A (RRID:CVCL_C5T4)
Comments	From: The Francis Crick Institute Limited; London; United Kingdom. Donor information: At sampling donor was not affected with Parkinson disease but at risk for disease. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11138; SNCA; Simple; p.Gly51Asp (c.152G>A); ClinVar=VCV000097000; Zygosity=Heterozygous (PubMed=37336145).
Disease	Parkinson disease 1, autosomal dominant (NCIt: C198602) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	57Y
Category	Induced pluripotent stem cell
Publications	PubMed=37336145; DOI=10.1016/j.scr.2023.103134 Devito L.G., Zanjani Z.S., Evans J.R., Scardamaglia A., Houlden H., Gandhi S., Healy L.E. Generation of two G51D SNCA missense mutation iPSC lines (CRICKi011-A, CRICKi012-A) from two individuals at risk of Parkinson's disease. Stem Cell Res. 71:103134-103134(2023)
Cell line databases/resources	hPSCreg; CRICKi012-A
Biological sample resources	BioSamples; SAMEA112233748
Encyclopedic resources	Wikidata; Q116048795
Entry history
Entry creation	15-Dec-2022
Last entry update	19-Dec-2024
Version number	4