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Cellosaurus CHO Pro-4 MtxRI OuaR-6-3 (CVCL_C5SD)

[Text version]
Cell line name CHO Pro-4 MtxRI OuaR-6-3
Synonyms Pro-4 MtxRI OuaR 6-3; Pro-4 MtxRIOuaR6-3
Accession CVCL_C5SD
Resource Identification Initiative To cite this cell line use: CHO Pro-4 MtxRI OuaR-6-3 (RRID:CVCL_C5SD)
Comments Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
Selected for resistance to: ChEBI; CHEBI_44185; Methotrexate (MTX).
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_C5RR (CHO Pro-4)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=1035580; DOI=10.1007/BF02835450
Flintoff W.F., Spindler S.M., Siminovitch L.
Genetic characterization of methotrexate-resistant chinese hamster ovary cells.
In Vitro 12:749-757(1976)

PubMed=7003776; DOI=10.1007/BF01539153
Flintoff W.F., Weber M.
Selection of wild-type revertants from methotrexate-resistant cells containing an altered dihydrofolate reductase.
Somatic Cell Genet. 6:517-528(1980)

Cross-references
Encyclopedic resources Wikidata; Q116048756
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5