ID   HepG2/CD81++
AC   CVCL_C5RP
DR   Wikidata; Q116049313
RX   PubMed=16819966;
CC   Population: Caucasian.
CC   Characteristics: Expresses 4 times more CD81 than HepG2-CD81 (Cellosaurus=CVCL_C5RN) (PubMed=16819966).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Transfected with: HGNC; 1701; CD81.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C3728; Hepatoblastoma
DI   ORDO; Orphanet_449; Hepatoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0027 ! Hep-G2
SX   Male
AG   15Y
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 29-06-23; Version: 3
//
RX   PubMed=16819966; DOI=10.1111/j.1462-5822.2006.00697.x;
RA   Silvie O., Greco C., Franetich J.-F., Dubart-Kupperschmitt A.,
RA   Hannoun L., van Gemert G.-J., Sauerwein R.W., Levy S., Boucheix C.,
RA   Rubinstein E., Mazier D.;
RT   "Expression of human CD81 differently affects host cell susceptibility
RT   to malaria sporozoites depending on the Plasmodium species.";
RL   Cell. Microbiol. 8:1134-1146(2006).
//