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Cellosaurus Mel-NT2-00 (CVCL_C531)

[Text version]
Cell line name Mel-NT2-00
Accession CVCL_C531
Resource Identification Initiative To cite this cell line use: Mel-NT2-00 (RRID:CVCL_C531)
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*02:01,03:01
HLA-BB*14:02,44:02:01:01
HLA-CC*05:01,08:02
Class II
HLA-DPDPB1*02:01:02,04:01
HLA-DQDQB1*03:01:01,04:02
HLA-DRDRB1*13:03,08:01
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-100

Markers:
AmelogeninX,Y
CSF1PO11
D3S135814,18
D5S81811,12
D7S82010,12
D13S31710,12
FGA20,23
TH016,7
TPOX11
vWA18,19

Run an STR similarity search on this cell line
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C531
ESTDAB; ESTDAB-100
Encyclopedic resources Wikidata; Q54905120
Polymorphism and mutation databases Cosmic; 2163815
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number14