| Cell line name |
Mel-NT1-00 |
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| Accession |
CVCL_C530 |
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| Resource Identification Initiative |
To cite this cell line use: Mel-NT1-00 (RRID:CVCL_C530) |
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| Sequence variations |
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Val95_His97del (c.286_294del) (p.Gly110fs, c.329_337del); Zygosity=Unspecified (PubMed=23851445).
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| HLA typing |
Source: PubMed=15592718
| Class I | | HLA-A | A*01:01,03:01 | | HLA-B | B*35:01,57:01 | | Class II | | HLA-DP | DPB1*04:01 | | HLA-DQ | DQB1*03:01:01,05:01 | | HLA-DR | DRB1*01:01,11:01:01 |
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| Disease |
Melanoma (NCIt: C3224) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Category |
Cancer cell line |
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| STR profile |
Source(s): ESTDAB=ESTDAB-115
Markers:
Run an STR similarity search on this cell line |
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| Publications | PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A., Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G., Garrido F.
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005) PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_C530
ESTDAB; ESTDAB-115
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| Encyclopedic resources |
Wikidata; Q54905119
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| Polymorphism and mutation databases |
Cosmic; 2163825
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 14 |
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