ID   2102EP
AC   CVCL_C522
SY   2102Ep; 2102 Ep; 2,102 Ep
DR   BTO; BTO:0005287
DR   EFO; EFO_0002957
DR   Cosmic; 2077185
DR   Cosmic; 2163762
DR   PRIDE; PXD030251
DR   Wikidata; Q54583213
RX   PubMed=6169654;
RX   PubMed=7095898;
RX   PubMed=7471097;
RX   PubMed=17284651;
RX   PubMed=20428235;
RX   PubMed=24812411;
RX   PubMed=35084545;
CC   Omics: Array-based CGH.
CC   Omics: Deep quantitative proteome analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Testis; UBERON=UBERON_0000473.
DI   NCIt; C3752; Embryonal carcinoma
DI   ORDO; Orphanet_180226; Embryonal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C523 ! 2102ER
SX   Male
AG   23Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 30-01-24; Version: 17
//
RX   PubMed=6169654; DOI=10.1002/ijc.2910260304;
RA   Andrews P.W., Bronson D.L., Benham F.J., Strickland S., Knowles B.B.;
RT   "A comparative study of eight cell lines derived from human testicular
RT   teratocarcinoma.";
RL   Int. J. Cancer 26:269-280(1980).
//
RX   PubMed=7095898; DOI=10.1002/ijc.2910290507;
RA   Andrews P.W., Goodfellow P.N., Shevinsky L.H., Bronson D.L.,
RA   Knowles B.B.;
RT   "Cell-surface antigens of a clonal human embryonal carcinoma cell
RT   line: morphological and antigenic differentiation in culture.";
RL   Int. J. Cancer 29:523-531(1982).
//
RX   PubMed=7471097;
RA   Wang N., Trend B., Bronson D.L., Fraley E.E.;
RT   "Nonrandom abnormalities in chromosome 1 in human testicular
RT   cancers.";
RL   Cancer Res. 40:796-802(1980).
//
RX   PubMed=17284651; DOI=10.1634/stemcells.2006-0236;
RA   Josephson R., Ording C.J., Liu Y., Shin S., Lakshmipathy U.,
RA   Toumadje A., Love B., Chesnut J.D., Andrews P.W., Rao M.S.,
RA   Auerbach J.M.;
RT   "Qualification of embryonal carcinoma 2102Ep as a reference for human
RT   embryonic stem cell research.";
RL   Stem Cells 25:437-446(2007).
//
RX   PubMed=20428235; DOI=10.1371/journal.pone.0010263;
RA   Hovatta O., Jaconi Devaud M.E.E., Tohonen V., Sloan-Bena F., Gimelli S.,
RA   Bosman A.G., Holm F., Wyder S., Zdobnov E.M., Irion O., Andrews P.W.,
RA   Antonarakis S.E., Zucchelli M., Kere J., Feki A.;
RT   "A teratocarcinoma-like human embryonic stem cell (hESC) line and four
RT   hESC lines reveal potentially oncogenic genomic changes.";
RL   PLoS ONE 5:E10263-E10263(2010).
//
RX   PubMed=24812411; DOI=10.1158/1078-0432.CCR-13-2868;
RA   Feldman D.R., Iyer G., Van Alstine L., Patil S., Al-Ahmadie H.,
RA   Reuter V.E., Bosl G.J., Chaganti R.S.K., Solit D.B.;
RT   "Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but
RT   not BRAF in cisplatin-resistant germ cell tumors.";
RL   Clin. Cancer Res. 20:3712-3720(2014).
//
RX   PubMed=35084545; DOI=10.1007/s00345-022-03936-1;
RA   Fichtner A., Bohnenberger H., Elakad O., Richter A., Lenz C., Oing C.,
RA   Strobel P., Kueffer S., Nettersheim D., Bremmer F.;
RT   "Proteomic profiling of cisplatin-resistant and cisplatin-sensitive
RT   germ cell tumour cell lines using quantitative mass spectrometry.";
RL   World J. Urol. 40:373-383(2022).
//