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Cellosaurus N1E-115 GFP-ADNP p.Tyr718* (CVCL_C4S2)

[Text version]
Cell line name N1E-115 GFP-ADNP p.Tyr718*
Accession CVCL_C4S2
Resource Identification Initiative To cite this cell line use: N1E-115 GFP-ADNP p.Tyr718* (RRID:CVCL_C4S2)
Comments Characteristics: Using CRISPR/Cas9 a GFP tag was integrated in the N-terminus of ADNP (PubMed=36230962).
Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Derived from site: In situ; Peripheral nervous system; UBERON=UBERON_0000010.
Cell type: Neural crest derived neuroblast; CL=CL_0002676.
Sequence variations
  • Mutation; MGI; MGI:1338758; Adnp; Simple_edited; p.Tyr418Ter; Zygosity=Homozygous; Note=By CRISPR/Cas9 (PubMed=36230962).
Disease Mouse neuroblastoma (NCIt: C21993)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: A/J.
Hierarchy Parent: CVCL_0451 (N1E-115)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=36230962; DOI=10.3390/cells11192994; PMCID=PMC9563912
Ganaiem M., Karmon G., Ivashko-Pachima Y., Gozes I.
Distinct impairments characterizing different ADNP mutants reveal aberrant cytoplasmic-nuclear crosstalk.
Cells 11:2994.1-2994.14(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049856
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number5