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Cellosaurus FL5.12 Bcl-XL (CVCL_C4LY)

[Text version]
Cell line name FL5.12 Bcl-XL
Synonyms FL5.12/Bcl-xL; FL5.12.Flag-Bcl-XL
Accession CVCL_C4LY
Resource Identification Initiative To cite this cell line use: FL5.12 Bcl-XL (RRID:CVCL_C4LY)
Comments Characteristics: IL3 dependent (from parent cell line).
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:88139; Bcl2l1 (Note=Isoform Bcl-XL with a N-terminal FLAG tag).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Embryonic liver; UBERON=UBERON_0002107.
Cell type: Pro-B cell; CL=CL_0000826.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_0262 (FL5.12)
Sex of cell Sex unspecified
Age at sampling 13FD
Category Factor-dependent cell line
Publications

PubMed=8798452; DOI=10.1074/jbc.271.37.22764
Simonian P.L., Grillot D.A.M., Merino R., Nunez G.
Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL.
J. Biol. Chem. 271:22764-22772(1996)

Cross-references
Encyclopedic resources Wikidata; Q116049014
Entry history
Entry creation15-Dec-2022
Last entry update10-Sep-2024
Version number4