Cellosaurus HeLa HFT/TO-PRKN PINK1-/- (CVCL_C4ES)
| Cell line name | HeLa HFT/TO-PRKN PINK1-/- |
|---|---|
| Accession | CVCL_C4ES |
| Resource Identification Initiative | To cite this cell line use: HeLa HFT/TO-PRKN PINK1-/- (RRID:CVCL_C4ES) |
| Comments | Population: African American. Knockout cell: Method=TALEN; HGNC; 14581; PINK1. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 8607; PRKN (Note=With 3xFLAG and HA tags). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00722; Escherichia coli beta-galactosidase (lacZ). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C4EQ (HeLa HFT/TO-PRKN) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=25284222; DOI=10.1016/j.molcel.2014.09.007; PMCID=PMC4254048 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116049308 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 5 |