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Cellosaurus Dig 40-150 (CVCL_C4DS)

[Text version]
Cell line name Dig 40-150
Synonyms 40-150
Accession CVCL_C4DS
Resource Identification Initiative To cite this cell line use: Dig 40-150 (RRID:CVCL_C4DS)
Comments Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: ChEBI; CHEBI:4551; Digoxin.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Children:
CVCL_C4DT (Dig 40-150 A2.4)
Category Hybridoma
Publications

PubMed=4033667; DOI=10.1016/0161-5890(85)90132-4
Mudgett-Hunter M., Anderson W., Haber E., Margolies M.N.
Binding and structural diversity among high-affinity monoclonal anti-digoxin antibodies.
Mol. Immunol. 22:477-488(1985)

PubMed=3129726; DOI=10.1073/pnas.85.9.3080; PMCID=PMC280147
Panka D.J., Mudgett-Hunter M., Parks D.R., Peterson L.L., Herzenberg L.A., Haber E., Margolies M.N.
Variable region framework differences result in decreased or increased affinity of variant anti-digoxin antibodies.
Proc. Natl. Acad. Sci. U.S.A. 85:3080-3084(1988)

PubMed=1565100; DOI=10.1016/0161-5890(92)90010-u
Shaw S.-Y., Margolies M.N.
A spontaneous variant of an antidigoxin hybridoma antibody with increased affinity arises from a heavy chain signal peptide mutation.
Mol. Immunol. 29:525-529(1992)

Cross-references
Biological sample resources ABCD; ABCD_AE886
Encyclopedic resources Wikidata; Q116048837
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2