Cellosaurus cell line UMB1949 (CVCL

Cellosaurus UMB1949 (CVCL_C471)

[Text version]

Cell line name

UMB1949

Synonyms

UMBSVtel

Accession

CVCL_C471

Resource Identification Initiative

To cite this cell line use: UMB1949 (RRID:CVCL_C471)

Comments

Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.

Sequence variations

Mutation; HGNC; HGNC:12363; TSC2; Simple; p.Val1362Leufs*50 (c.4083_4087delAGTCG); ClinVar=VCV000049741; Zygosity=Unspecified (PubMed=17592550).

Disease

Kidney angiomyolipoma (NCIt: C3888)
Tuberous sclerosis 2 (NCIt: C75331)
Tuberous sclerosis complex (ORDO: Orphanet_805)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

36Y

Category

Transformed cell line

STR profile

Source(s): ATCC=CRL-4004

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D2S1338	17,19
D3S1358	15,18
D5S818	11
D7S820	9,10
D8S1179	13,14
D13S317	12,13
D16S539	12
D18S51	16,17
D19S433	14
D21S11	28,30
FGA	23
Penta D	10,13
Penta E	5,7
TH01	6,8
TPOX	12
vWA	18

Publications

PubMed=17592550; DOI=10.2119/2006-00070.Lim; PMCID=PMC1892760
Lim S.D., Stallcup W.B., Lefkove B., Govindarajan B., Au K.S., Northrup H., Lang D., Fisher D.E., Patel A., Amin M.B., Arbiser J.L.
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Mol. Med. 13:160-165(2007)

Cross-references

Cell line collections (Providers)

ATCC; CRL-4004

Biological sample resources

BioSample; SAMN03471715

Encyclopedic resources

Wikidata; Q54991071

Entry history

Entry creation

22-Oct-2012

Last entry update

19-Dec-2024

Version number