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Cellosaurus CP-D (CVCL_C454)

[Text version]
Cell line name CP-D
Synonyms CP-D hTRT; CP-18821 hTERT
Accession CVCL_C454
Resource Identification Initiative To cite this cell line use: CP-D (RRID:CVCL_C454)
Comments Doubling time: ~39 hours (ATCC=CRL-4030).
Karyotypic information: Has lost chromosome Y.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Genome sequenced.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
Cell type: Epithelial cell of esophagus; CL=CL_0002252.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser303Alafs*42 (c.906del); Zygosity=Unspecified (from parent cell line).
Disease Barrett esophagus (NCIt: C2891)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A8WD (CP-18821)
Sex of cell Male
Age at sampling Adult
Category Telomerase immortalized cell line
STR profile Source(s): ATCC=CRL-4030

Markers:
AmelogeninX
CSF1PO12
D2S133823,25
D3S135815,16
D5S8189,12
D7S82010,11
D8S117911,15
D13S31712
D16S53910,13
D18S5113,16
D19S43315,15.2
D21S1129,32.2
FGA20,22
Penta D12,13
Penta E10
TH019,9.3
TPOX8
vWA16

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Publications

PubMed=12807723; DOI=10.1093/carcin/bgg076; PMCID=PMC1559990
Palanca-Wessels M.C.A., Klingelhutz A.J., Reid B.J., Norwood T.H., Opheim K.E., Paulson T.G., Feng Z.-D., Rabinovitch P.S.
Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model.
Carcinogenesis 24:1183-1190(2003)

PubMed=27594985; DOI=10.12688/f1000research.7033.1; PMCID=PMC4991527
Contino G., Eldridge M.D., Secrier M., Bower L., Elliott R.F., Weaver J., Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.
F1000Research 5:1336.1-1336.12(2016)

Cross-references
Cell line collections (Providers) ATCC; CRL-4030
Biological sample resources BioSample; SAMN03471733
Encyclopedic resources Wikidata; Q54814365
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number18