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Cellosaurus UKRV-Mel-30 (CVCL_C407)

[Text version]
Cell line name UKRV-Mel-30
Accession CVCL_C407
Resource Identification Initiative To cite this cell line use: UKRV-Mel-30 (RRID:CVCL_C407)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503; PubMed=23851445).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.242_243CC>TT (-138/-139CC>TT); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-146

Markers:
AmelogeninX
CSF1PO11
D3S135814
D5S81812,14
D7S82010,12
D13S31712
FGA21,24
TH019.3
TPOX8,10
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T., Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C407
ESTDAB; ESTDAB-146
Encyclopedic resources Wikidata; Q54990627
Polymorphism and mutation databases Cosmic; 1846723
Cosmic; 2163836
Cosmic; 2686536
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number17