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Cellosaurus SC34.28 (CVCL_C3YI)

[Text version]
Cell line name SC34.28
Accession CVCL_C3YI
Resource Identification Initiative To cite this cell line use: SC34.28 (RRID:CVCL_C3YI)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized antibody tamrintamab (hSC34.28) which when conjugated to a pyrrolobenzodiazepine dimer is known as tamrintamab pamozirine (SC-003) and is used in clinical trials for the treatment of ovarian carcinoma.
Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: UniProtKB; Q9H4B8; Human DPEP3.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

Patent=US10189910
Saunders L., Rokkam D., Liu D., Boontanrart M.
Anti-DPEP3 antibodies and methods of use.
Patent number US10189910, 29-Jan-2019

Cross-references
Biological sample resources ABCD; ABCD_AP829
Encyclopedic resources Wikidata; Q116050399
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2