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Cellosaurus 52M51 (CVCL_C3X1)

[Text version]
Cell line name 52M51
Accession CVCL_C3X1
Resource Identification Initiative To cite this cell line use: 52M51 (RRID:CVCL_C3X1)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-9405.
Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized brontictuzumab (OMP-52M51; 52M51H4L3) therapeutic antibody which was used in clinical trials for the treatment of lymphoid malignancies.
Monoclonal antibody isotype: Not specified.
Monoclonal antibody target: UniProtKB; P46531; Human NOTCH1.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Category Hybridoma
Publications

Patent=US8435513
Gurney A.L., Hoey T., Fitch-Bruhns M., Axelrod F.T.
NOTCH1 receptor antibodies and methods of treatment.
Patent number US8435513, 07-May-2013

Cross-references
Biological sample resources ABCD; ABCD_AF832
Encyclopedic resources Wikidata; Q116048264
Entry history
Entry creation15-Dec-2022
Last entry update21-Mar-2023
Version number2