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Cellosaurus PK15S10-CD163 (CVCL_C3VJ)

[Text version]
Cell line name PK15S10-CD163
Synonyms PK15(S10-CD163)
Accession CVCL_C3VJ
Resource Identification Initiative To cite this cell line use: PK15S10-CD163 (RRID:CVCL_C3VJ)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome (PRRSV).
Genetic integration: Method=Transfection/transduction; Gene=VGNC; VGNC:112737; CD163.
Genetic integration: Method=Transfection/transduction; Gene=VGNC; VGNC:112760; SIGLEC10.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Hampshire; VBO=VBO_0001146.
Hierarchy Parent: CVCL_C3VI (PK15S10)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=30021620; DOI=10.1186/s13567-018-0569-z; PMCID=PMC6052533
Xie J.-X., Christiaens I., Yang B., Trus I., Devriendt B., Cui T.-T., Wei R.-F., Nauwynck H.J.
Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15(S1-CD163) and PK15(S10-CD163) cells.
Vet. Res. 49:67.1-67.13(2018)

PubMed=34205087; DOI=10.3390/vaccines9060594; PMCID=PMC8229515
Xie J.-X., Vereecke N., Theuns S., Oh D.-Y., Vanderheijden N., Trus I., Sauer J., Vyt P., Bonckaert C., Lalonde C., Provost C., Gagnon C.A., Nauwynck H.J.
Comparison of primary virus isolation in pulmonary alveolar macrophages and four different continuous cell lines for type 1 and type 2 porcine reproductive and respiratory syndrome virus.
Vaccines (Basel) 9:594.1-594.13(2021)

Cross-references
Encyclopedic resources Wikidata; Q116050123
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5