Cellosaurus HEK-Blue hACE2-TMPRSS2 (CVCL_C3S5)
| Cell line name | HEK-Blue hACE2-TMPRSS2 |
|---|---|
| Accession | CVCL_C3S5 |
| Resource Identification Initiative | To cite this cell line use: HEK-Blue hACE2-TMPRSS2 (RRID:CVCL_C3S5) |
| Comments | Group: SARS-CoV-2 research cell line. Characteristics: SEAP (secreted ALPP) reporter cell line, in this cell line SEAP is under the control of an IFN-beta minimal promoter fused to 5 NF-kappaB and AP-1-binding sites. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 439; ALPP. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 13557; ACE2. Genetic integration: Method=Transfection/transduction; Gene=HGNC; 11876; TMPRSS2. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_A7YK (HEK-Blue hACE2) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | https://www.invivogen.com/hek-blue-hace2-tmprss2-cells |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116049297 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 10-Sep-2024 |
| Version number | 5 |