Cellosaurus cell line ICGi043-A (CVCL

Cross-references
Cell line name	ICGi043-A
Synonyms	LR-21
Accession	CVCL_C3RW
Resource Identification Initiative	To cite this cell line use: ICGi043-A (RRID:CVCL_C3RW)
Comments	From: The Federal Research Center Institute of Cytology and Genetics; Novosibirsk; Russia. Population: Caucasian. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; 18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (DOI=10.1134/S1062360423010058).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_C3RX ! ICGi043-B CVCL_C3RY ! ICGi043-C
Sex of cell	Female
Age at sampling	74Y
Category	Induced pluripotent stem cell
Publications	DOI=10.1134/S1062360423010058 Grigor'eva E.V., Pavlova S.V., Malakhova A.A., Yarkova E.S., Sorogina D.A., Minina J.M., Miliukhina I.V., Nikolaev M.A., Pchelina S.N., Medvedev S.P., Zakian S.M. Generation of an induced pluripotent stem cell line, ICGi043-A, by reprogramming peripheral blood mononuclear cells from a Parkinson's disease patient with p.G2019S mutation in the LRRK2 gene. Russ. J. Dev. Biol. 54:72-79(2023)
Cell line databases/resources	hPSCreg; ICGi043-A
Biological sample resources	BioSamples; SAMEA111344463
Encyclopedic resources	Wikidata; Q117704514
Entry history
Entry creation	21-Mar-2023
Last entry update	10-Sep-2024
Version number	3