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Cellosaurus HEK293 GOT2 KO clone A7 (CVCL_C3NI)

[Text version]
Cell line name HEK293 GOT2 KO clone A7
Accession CVCL_C3NI
Resource Identification Initiative To cite this cell line use: HEK293 GOT2 KO clone A7 (RRID:CVCL_C3NI)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4433; GOT2.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=31422819; DOI=10.1016/j.ajhg.2019.07.015; PMCID=PMC6732527
van Karnebeek C.D.M., Ramos R.J., Wen X.-Y., Tarailo-Graovac M., Gleeson J.G., Skrypnyk C., Brand-Arzamendi K., Karbassi F., Issa M.Y., van der Lee R., Drogemoller B.I., Koster J., Rousseau J., Campeau P.M., Wang Y.-D., Cao F., Li M., Ruiter J., Ciapaite J., Kluijtmans L.A.J., Willemsen M.A.A.P., Jans J.J.M., Ross C.J.D., Wintjes L.T., Rodenburg R.J., Huigen M.C.D.G., Jia Z.-P., Waterham H.R., Wasserman W.W., Wanders R.J.A., Verhoeven-Duif N.M., Zaki M.S., Wevers R.A.
Bi-allelic GOT2 mutations cause a treatable malate-aspartate shuttle-related encephalopathy.
Am. J. Hum. Genet. 105:534-548(2019)

Cross-references
Cell line collections (Providers) ABM; T6426
Encyclopedic resources Wikidata; Q116049301
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number4