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Cellosaurus MVX-2 (CVCL_C3LY)

[Text version]
Cell line name MVX-2
Synonyms MaxiVaX-2; huGM-CSF clone 61.27; Clone #61.27
Accession CVCL_C3LY
Resource Identification Initiative To cite this cell line use: MVX-2 (RRID:CVCL_C3LY)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Culture Collection of Switzerland (CCOS); CCOS-1901.
Characteristics: Expression of CSF2 is under the control of a PGK promoter (PubMed=36092361).
Doubling time: 37 hours (Direct_author_submission).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:2434; CSF2.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Miscellaneous: Cell line name and doubling time from personal communication of Lathuiliere, Aurelien.
Derived from site: In situ; Muscle, semitendinosus; UBERON=UBERON_0001375.
Cell type: Myoblast; CL=CL_0000056.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3LX (IHM-2)
Sex of cell Female
Age at sampling 32Y
Category Telomerase immortalized cell line
Publications

Patent=US20220265727
Lathuiliere A., Mach N., Salmon P.
Immortalized myoblast cell lines and uses thereof.
Patent number US20220265727, 25-Aug-2022

PubMed=36092361; DOI=10.1016/j.omtm.2022.07.017; PMCID=PMC9418741
Lathuiliere A., Vernet R., Charrier E., Urwyler M., Von Rohr O., Belkouch M.-C., Saingier V., Bouvarel T., Guillarme D., Engel A., Salmon P., Laumonier T., Grogg J., Mach N.
Immortalized human myoblast cell lines for the delivery of therapeutic proteins using encapsulated cell technology.
Mol. Ther. Methods Clin. Dev. 26:441-458(2022)

Cross-references
Encyclopedic resources Wikidata; Q116049838
Entry history
Entry creation15-Dec-2022
Last entry update19-Dec-2024
Version number5