ID   SH-SY5Y-parkin clone 6
AC   CVCL_C3I8
SY   SH-Parkin 6
DR   cancercelllines; CVCL_C3I8
DR   Wikidata; Q114312999
RX   PubMed=16278233;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
CC   Transfected with: HGNC; 8607; PRKN (with a N-terminal FLAG tag).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C3270; Neuroblastoma
DI   ORDO; Orphanet_635; Neuroblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0019 ! SH-SY5Y
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=16278233; DOI=10.1093/hmg/ddi413;
RA   Wang C., Ko H.S., Thomas B., Tsang F., Chew K.C.M., Tay S.-P.,
RA   Ho M.W.L., Lim T.-M., Soong T.-W., Pletnikova O., Troncoso J., Dawson V.L.,
RA   Dawson T.M., Lim K.-L.;
RT   "Stress-induced alterations in parkin solubility promote parkin
RT   aggregation and compromise parkin's protective function.";
RL   Hum. Mol. Genet. 14:3885-3897(2005).
//