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Cellosaurus SW780 FOXP3Delta3 (CVCL_C3GW)

[Text version]
Cell line name SW780 FOXP3Delta3
Synonyms SW780 FOXP3 Delta 3
Accession CVCL_C3GW
Resource Identification Initiative To cite this cell line use: SW780 FOXP3Delta3 (RRID:CVCL_C3GW)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6106; FOXP3 (Note=Isoform Delta3).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1728 (SW780)
Sex of cell Female
Age at sampling 80Y
Category Cancer cell line
Publications

PubMed=27189164; DOI=10.1158/1078-0432.CCR-15-2581
Zhang H.-W., Prado K., Zhang K.X., Peek E.M., Lee J., Wang X.-Y., Huang J.-T., Li G., Pellegrini M., Chin A.I.
Biased expression of the FOXP3Delta3 isoform in aggressive bladder cancer mediates differentiation and cisplatin chemotherapy resistance.
Clin. Cancer Res. 22:5349-5361(2016)

Cross-references
Encyclopedic resources Wikidata; Q114313077
Gene expression databases GEO; GSM2143921
GEO; GSM2143922
GEO; GSM2143923
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7