| Cell line name |
Ishikawa 3-H-12 PRA-14 |
|---|
| Synonyms |
PRA-14 |
|---|
| Accession |
CVCL_C3G7 |
|---|
| Resource Identification Initiative |
To cite this cell line use: Ishikawa 3-H-12 PRA-14 (RRID:CVCL_C3G7) |
|---|
| Comments |
Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 8910; PGR (Note=Isoform A).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
|---|
| Sequence variations |
- Mutation; HGNC; 8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
|---|
| Disease |
Endometrial adenocarcinoma (NCIt: C7359) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_D199 (Ishikawa 3-H-12) |
|---|
| Sex of cell |
Female |
|---|
| Age at sampling |
39Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=12517594; DOI=10.1177/107155760301000110
Smid-Koopman E., Blok L.J., Kuhne L.C.M., Burger C.W., Helmerhorst T.J.M., Brinkmann A.O., Huikeshoven F.J.
Distinct functional differences of human progesterone receptors A and B on gene expression and growth regulation in two endometrial carcinoma cell lines.
J. Soc. Gynecol. Investig. 10:49-57(2003) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_C3G7
|
|---|
| Encyclopedic resources |
Wikidata; Q114311769
|
|---|
| Entry history |
|---|
| Entry creation | 22-Sep-2022 |
|---|
| Last entry update | 10-Sep-2024 |
|---|
| Version number | 6 |
|---|
