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Cellosaurus ASP1-UPIC (CVCL_C3G3)

[Text version]
Cell line name ASP1-UPIC
Synonyms Alport Syndrome Patient 1-Urine Podocyte Immortalized Cell line
Accession CVCL_C3G3
Resource Identification Initiative To cite this cell line use: ASP1-UPIC (RRID:CVCL_C3G3)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Omics: Transcriptome analysis by RNAseq.
Miscellaneous: As no cell line name was provided in the paper, we assigned the name based on the abbreviation of the cell line description.
Derived from site: In situ; Urine; UBERON=UBERON_0001088.
Cell type: Podocyte; CL=CL_0000653.
Sequence variations
Disease Alport syndrome (NCIt: C34842)
Alport syndrome (ORDO: Orphanet_63)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 14Y
Category Conditionally immortalized cell line
Publications

PubMed=32652570; DOI=10.1002/path.5496; PMCID=PMC7589231
Iampietro C., Bellucci L., Arcolino F.O., Arigoni M., Alessandri L., Gomez Y., Papadimitriou E., Calogero R.A., Cocchi E., van den Heuvel L.P.W.J., Levtchenko E.N., Bussolati B.
Molecular and functional characterization of urine-derived podocytes from patients with Alport syndrome.
J. Pathol. 252:88-100(2020)

Cross-references
Encyclopedic resources Wikidata; Q114310630
Gene expression databases GEO; GSM3933297
GEO; GSM3933298
GEO; GSM3933299
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7