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Cellosaurus CWRU-C57BL/6 swe/swe-IPTEC (CVCL_C3FD)

[Text version]
Cell line name CWRU-C57BL/6 swe/swe-IPTEC
Synonyms Case Western Reserve University-C57BL/6 swe/swe-Immortalized Proximal Tubule Epithelial Cell line
Accession CVCL_C3FD
Resource Identification Initiative To cite this cell line use: CWRU-C57BL/6 swe/swe-IPTEC (RRID:CVCL_C3FD)
Comments Knockout cell: Method=KO mouse; MGI; MGI:102462; Slc9a1.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Miscellaneous: As no cell line name was provided in the paper, we assigned the name based on the abbreviation of the institution and of the cell line description.
Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.SJL swe/swe.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=22020933; DOI=10.1074/jbc.M110.212845; PMCID=PMC3234923
Abu Jawdeh B.G., Khan S., Deschenes I., Hoshi M., Goel M., Lock J.T., Shinlapawittayatorn K., Babcock G.T., Lakhe-Reddy S., DeCaro G.J., Yadav S.P., Mohan M.L., Naga Prasad S.V., Schilling W.P., Ficker E., Schelling J.R.
Phosphoinositide binding differentially regulates NHE1 Na+/H+ exchanger-dependent proximal tubule cell survival.
J. Biol. Chem. 286:42435-42445(2011)

PubMed=24531551; DOI=10.1172/JCI71863; PMCID=PMC3934167
Khan S., Abu Jawdeh B.G., Goel M., Schilling W.P., Parker M.D., Puchowicz M.A., Yadav S.P., Harris R.C., El-Meanawy A., Hoshi M., Shinlapawittayatorn K., Deschenes I., Ficker E., Schelling J.R.
Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.
J. Clin. Invest. 124:1057-1068(2014)

Cross-references
Encyclopedic resources Wikidata; Q114311316
Entry history
Entry creation22-Sep-2022
Last entry update10-Sep-2024
Version number6