Cellosaurus A375 Safe Harbor Landing Pad (CVCL_C3EX)
| Cell line name | A375 Safe Harbor Landing Pad | ||||||||||||||||||
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| Accession | CVCL_C3EX | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: A375 Safe Harbor Landing Pad (RRID:CVCL_C3EX) | ||||||||||||||||||
| Comments | Population: Caucasian. Characteristics: Using ZFN a fluorescent mKATE2 tag flanked by Cre-lox sites (LoxN-EF1a-Lox2272-mKATE2-LoxP) was introduced in the AAVS1 safe harbor locus. The mKATE2 tag can be exchanged for a payload of the user's choice using Cre recombinase and a targeting vector with appropriate lox sites (Sigma-Aldrich=CLL1219). Doubling time: ~22 hours (Sigma-Aldrich=CLL1219). Genetic integration: Method=ZFN; Gene=FPbase; DBBO8; mKate2 (Note=Bright red fluorescent protein derived from eqFP578). Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511. | ||||||||||||||||||
| Sequence variations |
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| Disease | Amelanotic melanoma (NCIt: C3802) | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0132 (A-375) | ||||||||||||||||||
| Sex of cell | Female | ||||||||||||||||||
| Age at sampling | 54Y | ||||||||||||||||||
| Category | Cancer cell line | ||||||||||||||||||
| STR profile | Source(s): Sigma-Aldrich=CLL1219 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | Sigma-Aldrich; CLL1219 | ||||||||||||||||||
| Cell line databases/resources | cancercelllines; CVCL_C3EX | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q114310508 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 22-Sep-2022 | ||||||||||||||||||
| Last entry update | 10-Sep-2024 | ||||||||||||||||||
| Version number | 6 | ||||||||||||||||||