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Cellosaurus Raji HLA-B*07:02 (CVCL_C3D5)

[Text version]
Cell line name Raji HLA-B*07:02
Accession CVCL_C3D5
Resource Identification Initiative To cite this cell line use: Raji HLA-B*07:02 (RRID:CVCL_C3D5)
Comments Population: African; Nigerian.
Characteristics: Transduced with a lentiviral construct that contains a B2M-HLA-B fusion protein (Sigma-Aldrich=HLA001).
Knockout cell: Method=ZFN; HGNC; HGNC:914; B2M.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:914; B2M.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:4932; HLA-B (Note=Allele B*07:02).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw, maxilla; UBERON=UBERON_0002397.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Gene fusion; HGNC; HGNC:5477; IGH + HGNC; HGNC:7553; MYC; Name(s)=MYC-IGH (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Gln (c.638G>A); ClinVar=VCV000135359; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234His (c.700T>C); ClinVar=VCV000376691; Zygosity=Heterozygous (from parent cell line).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C3CD (Raji B2M KO)
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Sigma-Aldrich; HLA001
Cell line databases/resources cancercelllines; CVCL_C3D5
Encyclopedic resources Wikidata; Q114312763
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number8