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Cellosaurus UKRV-Mel-15b (CVCL_C397)

[Text version]
Cell line name UKRV-Mel-15b
Accession CVCL_C397
Resource Identification Initiative To cite this cell line use: UKRV-Mel-15b (RRID:CVCL_C397)
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-149C>T (c.253C>T) (C253T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A713 ! UKRV-Mel-15a
CVCL_C398 ! UKRV-Mel-15c
CVCL_A714 ! UKRV-Mel-15d
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-227

Markers:
AmelogeninX
CSF1PO11
D3S135815,16
D5S81811
D7S8208,12
D13S31711,12
FGA21,22
TH016
TPOX8,12
vWA15,17

Run an STR similarity search on this cell line
Publications

PubMed=23348503; DOI=10.1126/science.1230062
Horn S., Figl A., Rachakonda P.S., Fischer C., Sucker A., Gast A., Kadel S., Moll I., Nagore E., Hemminki K., Schadendorf D., Kumar R.
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C397
ESTDAB; ESTDAB-227
Encyclopedic resources Wikidata; Q54990596
Polymorphism and mutation databases Cosmic; 1846703
Cosmic; 2686516
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number15