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Cellosaurus I 3 (CVCL_C376)

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Cell line name I 3
Synonyms I3; Israel number 3; TE03; TE-03; ES-I3; hES I3; HESI3; TECHe001-A
Accession CVCL_C376
Resource Identification Initiative To cite this cell line use: I 3 (RRID:CVCL_C376)
Comments From: Technion - Israel Institute of Technology; Haifa; Israel.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0204.
Registration: Swiss research registry; BAG-hES-IMP-0005.
Omics: Deep exome analysis.
Omics: H3K27me3 ChIP-seq epigenome analysis.
Omics: H3K36me3 ChIP-seq epigenome analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K4me3 ChIP-seq epigenome analysis.
Omics: H3K9ac ChIP-seq epigenome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C377 (I 3.2)CVCL_C378 (I 3.3)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; WiCell=te03

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S82010,11
D13S31712,14
D16S53911,12
TH017,9
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages https://stemcelldb.nih.gov/cellLineDetails.do?id=8
Publications

PubMed=16919167; DOI=10.1186/1741-7007-4-28; PMCID=PMC1601965
Josephson R., Sykes G.R., Liu Y., Ording C.J., Xu W.-N., Zeng X.-M., Shin S., Loring J.F., Maitra A., Rao M.S., Auerbach J.M.
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F., Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Mallon B.S., Chenoweth J.G., Johnson K.R., Hamilton R.S., Tesar P.J., Yavatkar A.S., Tyson L.J., Park K., Chen K.G., Fann Y.C., McKay R.D.G.
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C., Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G., Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A., Eggan K.C.
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line collections (Providers) WiCell; te03
Cell line databases/resources hPSCreg; TECHe001-A
IGRhCellID; I3%20p41
NIHhESC; NIHhESC-13-0204
SKIP; SKIP001859
Anatomy/cell type resources BTO; BTO:0006059
Biological sample resources BioSample; SAMN03471893
ENCODE; ENCBS057COO
ENCODE; ENCBS058LJQ
ENCODE; ENCBS065EQG
ENCODE; ENCBS224XQX
ENCODE; ENCBS268NCC
ENCODE; ENCBS312JDV
ENCODE; ENCBS401QZO
ENCODE; ENCBS412HHB
ENCODE; ENCBS421TWG
ENCODE; ENCBS433JWB
ENCODE; ENCBS524MEF
ENCODE; ENCBS533SYQ
ENCODE; ENCBS593HOC
ENCODE; ENCBS599JGY
ENCODE; ENCBS682JTI
ENCODE; ENCBS811OSD
Encyclopedic resources Wikidata; Q54897060
Experimental variables resources EFO; EFO_0007076
Gene expression databases GEO; GSM537624
GEO; GSM537625
GEO; GSM537626
GEO; GSM537627
GEO; GSM537647
GEO; GSM537648
GEO; GSM537664
GEO; GSM537665
GEO; GSM537668
GEO; GSM537669
GEO; GSM537670
GEO; GSM537672
GEO; GSM621345
GEO; GSM621348
GEO; GSM621386
GEO; GSM772789
GEO; GSM856736
GEO; GSM981282
GEO; GSM981293
GEO; GSM1342462
GEO; GSM1342464
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number21