Cellosaurus cell line TYR1-hiPSC1 (CVCL

Cellosaurus TYR1-hiPSC1 (CVCL_C361)

Cross-references
Cell line name	TYR1-hiPSC1
Synonyms	TYR.1.H.iPSC.1; TYR1hiPSC1; T-hiPSC1; RIi005-A
Accession	CVCL_C361
Resource Identification Initiative	To cite this cell line use: TYR1-hiPSC1 (RRID:CVCL_C361)
Comments	From: Royan Institute; Theran; Iran. Population: Iranian. Omics: Proteome analysis by 2D-DE/MS. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:3579; FAH; Simple; p.Gln64His (c.192G>T); ClinVar=VCV000021054; Zygosity=Unspecified (PubMed=20821352).
Disease	Tyrosinemia type I (NCIt: C98641) Tyrosinemia type 1 (ORDO: Orphanet_882)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_C362 ! TYR1-hiPSC2 CVCL_C363 ! TYR1-hiPSC3 CVCL_C364 ! TYR1-hiPSC4 CVCL_C365 ! TYR1-hiPSC5 CVCL_C366 ! TYR1-hiPSC6 CVCL_C367 ! TYR1-hiPSC7
Sex of cell	Female
Age at sampling	6Y
Category	Induced pluripotent stem cell
Publications	PubMed=20821352; DOI=10.1007/s12015-010-9189-3 Ghodsizadeh A., Taei A., Totonchi M., Seifinejad A., Gourabi H., Pournasr B., Aghdami N., Malekzadeh R., Almadani N., Salekdeh G.H., Baharvand H. Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Stem Cell Rev. Rep. 6:622-632(2010) PubMed=22543856; DOI=10.1039/c2mb25018g Faradonbeh M.Z., Gharechahi J., Mollamohammadi S., Pakzad M., Taei A., Rassouli H., Baharvand H., Salekdeh G.H. An orthogonal comparison of the proteome of human embryonic stem cells with that of human induced pluripotent stem cells of different genetic background. Mol. Biosyst. 8:1833-1840(2012)
Cell line collections (Providers)	RSCB; RSCB0067
Cell line databases/resources	hPSCreg; RIi005-A SKIP; SKIP002400 SKIP; SKIP005840
Encyclopedic resources	Wikidata; Q54973479
Entry history
Entry creation	22-Oct-2012
Last entry update	19-Dec-2024
Version number	18