Cellosaurus logo
expasy logo

Cellosaurus Mel285 (CVCL_C303)

[Text version]
Cell line name Mel285
Synonyms MEL285; Mel-285; Mel 285
Accession CVCL_C303
Resource Identification Initiative To cite this cell line use: Mel285 (RRID:CVCL_C303)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: Ksander B.; Schepens Eye Research Institute; Boston; USA.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap; PubMed=22236444

Markers:
AmelogeninX
CSF1PO10,13
D3S135815,17
D5S81813
D7S8208,13
D8S117911,15
D13S31711
D16S53911,14
D18S5116,17
D21S1129
FGA20,22
Penta D5
Penta E17
TH018,9.3
TPOX11
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x
Griewank K.G., Yu X.-X., Khalili J., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by Gefitinib and Cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

PubMed=28018010
Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C303
Cell_Model_Passport; SIDM01793
DepMap; ACH-002015
Encyclopedic resources Wikidata; Q54905164
Polymorphism and mutation databases Cosmic; 916140
Cosmic; 1628405
Cosmic; 2036708
Entry history
Entry creation22-Oct-2012
Last entry update05-Oct-2023
Version number15