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Cellosaurus BEAS-2B IRF1 KO (CVCL_C2UN)

[Text version]
Cell line name BEAS-2B IRF1 KO
Synonyms BEAS-2B-IRF1 KO; IRF1 KO BEAS-2B
Accession CVCL_C2UN
Resource Identification Initiative To cite this cell line use: BEAS-2B IRF1 KO (RRID:CVCL_C2UN)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6116; IRF1.
Transformant: Ad12-SV40 hybrid virus.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Category Transformed cell line
Publications

PubMed=31156620; DOI=10.3389/fimmu.2019.01019; PMCID=PMC6529937
Panda D., Gjinaj E., Bachu M., Squire E., Novatt H., Ozato K., Rabin R.L.
IRF1 maintains optimal constitutive expression of antiviral genes and regulates the early antiviral response.
Front. Immunol. 10:1019.1-1019.16(2019)

Cross-references
Encyclopedic resources Wikidata; Q114310727
Gene expression databases GEO; GSM3138806
GEO; GSM3138807
GEO; GSM3138808
GEO; GSM3138809
GEO; GSM3138810
GEO; GSM3138811
GEO; GSM3138812
GEO; GSM3138813
GEO; GSM3138814
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number6