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Cellosaurus UPMM-1 (CVCL_C299)

[Text version]
Cell line name UPMM-1
Synonyms UPMM1; Uveal Primary Melanoma with Monosomy-3 1
Accession CVCL_C299
Resource Identification Initiative To cite this cell line use: UPMM-1 (RRID:CVCL_C299)
Comments Doubling time: 100-150 hours (PubMed=19212147).
Karyotypic information: Monosomy of chromosome 3 (PubMed=16750193).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22236444

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135818
D5S81811,12
D7S8208
D13S3179,11
D16S53913
FGA21
TH019,9.3
TPOX8,11
vWA15,16

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Publications

PubMed=16750193; DOI=10.1016/j.exer.2006.04.004
Nareyeck G., Zeschnigk M., Prescher G., Lohmann D.R., Anastassiou G.
Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3.
Exp. Eye Res. 83:858-864(2006)

PubMed=19212147; DOI=10.1159/000201566
Nareyeck G., Zeschnigk M., Bornfeld N., Anastassiou G.
Novel cell lines derived by long-term culture of primary uveal melanomas.
Ophthalmologica 223:196-201(2009)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

Cross-references
Cell line collections (Providers) Kerafast; EDE001
Cell line databases/resources cancercelllines; CVCL_C299
Encyclopedic resources Wikidata; Q54991706
Polymorphism and mutation databases Cosmic; 1628399
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16