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Cellosaurus UPMD-2 (CVCL_C298)

[Text version]
Cell line name UPMD-2
Synonyms UPMD2; Uveal Primary Melanoma with Disomy-3 2
Accession CVCL_C298
Resource Identification Initiative To cite this cell line use: UPMD-2 (RRID:CVCL_C298)
Comments Doubling time: 150 hours (PubMed=19212147).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22236444

Markers:
AmelogeninX
CSF1PO11
D3S135818
D5S81811
D7S8208
D13S31711,12
D16S5399,13
FGA24,25
TH016,9.3
TPOX8,11
vWA17,18

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Publications

PubMed=19212147; DOI=10.1159/000201566
Nareyeck G., Zeschnigk M., Bornfeld N., Anastassiou G.
Novel cell lines derived by long-term culture of primary uveal melanomas.
Ophthalmologica 223:196-201(2009)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C298
Encyclopedic resources Wikidata; Q54991704
Polymorphism and mutation databases Cosmic; 1628404
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16