ID   WM873-2
AC   CVCL_C285
SY   WM-873-2; WM 873-2; WML-873-2
DR   cancercelllines; CVCL_C285
DR   Rockland; WM873-2-01-0001
DR   Wikidata; Q54994331
RX   PubMed=2253310;
RX   PubMed=3856042;
RX   PubMed=4053039;
WW   https://www.wistar.org/our-scientists/meenhard-herlyn
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from autologous cell lines WM740V; WM858; WM873-1).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
ST   Source(s): Wistar
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 11
ST   D16S539: 8
ST   D18S51: 14
ST   D19S433: 13,15
ST   D21S11: 29,32.2
ST   D2S1338: 22,23
ST   D3S1358: 17
ST   D5S818: 10,12
ST   D7S820: 9,10
ST   D8S1179: 12,13
ST   FGA: 20,23
ST   TH01: 6,8
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_L030 ! WM740V
OI   CVCL_C283 ! WM858
OI   CVCL_C284 ! WM873-1
OI   CVCL_C286 ! WM873-3
SX   Female
AG   48Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 21
//
RX   PubMed=2253310; DOI=10.1007/BF00046337;
RA   Herlyn M.;
RT   "Human melanoma: development and progression.";
RL   Cancer Metastasis Rev. 9:101-112(1990).
//
RX   PubMed=3856042; DOI=10.1093/jnci/74.2.283;
RA   Herlyn M., Balaban-Malenbaum G.B., Bennicelli J.L., Guerry D. 4th,
RA   Halaban R., Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C.,
RA   Clark W.H. Jr., Koprowski H.;
RT   "Primary melanoma cells of the vertical growth phase: similarities to
RT   metastatic cells.";
RL   J. Natl. Cancer Inst. 74:283-289(1985).
//
RX   PubMed=4053039;
RA   Herlyn M., Thurin J., Balaban-Malenbaum G.B., Bennicelli J.L., Herlyn D.,
RA   Elder D.E., Bondi E., Guerry D. 4th, Nowell P.C., Clark W.H. Jr.,
RA   Koprowski H.;
RT   "Characteristics of cultured human melanocytes isolated from different
RT   stages of tumor progression.";
RL   Cancer Res. 45:5670-5676(1985).
//