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Cellosaurus WM8 (CVCL_C281)

[Text version]
Cell line name WM8
Synonyms WM-8; WM 8
Accession CVCL_C281
Resource Identification Initiative To cite this cell line use: WM8 (RRID:CVCL_C281)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D19S433: 12.2,15->15, D8S1179: 11,12,14->12,14 and FGA: 22->22,27.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:6342; KIT; Simple; p.Asn822Lys (c.2466T>A) (N818K); ClinVar=VCV000375931; Zygosity=Unspecified (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,23
D3S135815,16
D5S81812,13
D7S8209,13
D8S117912,14
D13S31711,12
D16S5399
D18S5119,20
D19S43315
D21S1130
FGA22,27
TH018
TPOX8,11
vWA16,19

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Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=286328; DOI=10.1073/pnas.76.3.1438; PMCID=PMC383267
Herlyn M., Steplewski Z., Herlyn D., Koprowski H.
Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies.
Proc. Natl. Acad. Sci. U.S.A. 76:1438-1442(1979)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM8-01-0001
Cell line databases/resources cancercelllines; CVCL_C281
Encyclopedic resources Wikidata; Q54994319
Gene expression databases GEO; GSM185206
GEO; GSM185207
GEO; GSM952610
Polymorphism and mutation databases Cosmic; 928683
Cosmic; 1155543
IARC_TP53; 24989
Progenetix; CVCL_C281
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number21