ID   WM3918
AC   CVCL_C279
SY   WM-3918; WM 3918
DR   cancercelllines; CVCL_C279
DR   GEO; GSM952608
DR   Progenetix; CVCL_C279
DR   Rockland; WM3918-01-0001
DR   Wikidata; Q54994303
RX   PubMed=24576830;
WW   https://www.wistar.org/our-scientists/meenhard-herlyn
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (Wistar).
CC   Omics: Transcriptome analysis by microarray.
CC   Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D18S51: 13->9,13 and FGA: 21,24->20,21,24.
CC   Derived from site: Metastatic; Not specified.
ST   Source(s): Wistar
ST   Amelogenin: X,Y
ST   CSF1PO: 12
ST   D13S317: 11
ST   D16S539: 10,13
ST   D18S51: 9,13
ST   D19S433: 14,16
ST   D21S11: 28,30
ST   D2S1338: 19,24
ST   D3S1358: 17
ST   D5S818: 11,12
ST   D7S820: 12
ST   D8S1179: 13,16
ST   FGA: 20,21,24
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 19
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RX   PubMed=24576830; DOI=10.1158/0008-5472.CAN-13-2625;
RA   Nissan M.H., Pratilas C.A., Jones A.M., Ramirez R., Won H., Liu C.-L.,
RA   Tiwari S., Kong L., Hanrahan A.J., Yao Z., Merghoub T., Ribas A.,
RA   Chapman P.B., Yaeger R., Taylor B.S., Schultz N., Berger M.F.,
RA   Rosen N., Solit D.B.;
RT   "Loss of NF1 in cutaneous melanoma is associated with RAS activation
RT   and MEK dependence.";
RL   Cancer Res. 74:2340-2350(2014).
//