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Cellosaurus WM373 (CVCL_C277)

[Text version]
Cell line name WM373
Synonyms WM-373; WM 373
Accession CVCL_C277
Resource Identification Initiative To cite this cell line use: WM373 (RRID:CVCL_C277)
Comments Part of: Wistar Institute melanoma cell line collection.
Characteristics: Pigmented.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7156 ! WM75
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133817
D3S135814
D5S81811
D7S8208
D8S117913
D13S31712
D16S53912,13
D18S5114,16
D19S43312,14
D21S1129
FGA20
TH016
TPOX9,11
vWA17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Herlyn M., Balaban-Malenbaum G.B., Bennicelli J.L., Guerry D. 4th, Halaban R., Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C., Clark W.H. Jr., Koprowski H.
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Herlyn M., Thurin J., Balaban-Malenbaum G.B., Bennicelli J.L., Herlyn D., Elder D.E., Bondi E., Guerry D. 4th, Nowell P.C., Clark W.H. Jr., Koprowski H.
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM373-01-0001
Cell line databases/resources cancercelllines; CVCL_C277
Encyclopedic resources Wikidata; Q54994291
Polymorphism and mutation databases Cosmic; 928687
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number22