ID   WM1791A
AC   CVCL_C267
SY   WM-1791A; WM 1791A; WM 1791-A; EST74
DR   cancercelllines; CVCL_C267
DR   Cosmic; 1047653
DR   ESTDAB; ESTDAB-074
DR   GEO; GSM156013
DR   IARC_TP53; 26080
DR   Progenetix; CVCL_C267
DR   Wikidata; Q54994195
RX   PubMed=2253310;
RX   PubMed=15592718;
RX   PubMed=17260012;
RX   PubMed=19340423;
RX   PubMed=23851445;
CC   Part of: Wistar Institute melanoma cell line collection.
CC   HLA typing: A*02:01; B*07:02,44:02; C*07:02,05:01; DPB1*06:01,19:01; DQB1*06:02,03:01:01; DRB1*15:01,ND (PubMed=15592718).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=17260012; PubMed=23851445).
CC   Omics: Array-based CGH.
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
ST   Source(s): ESTDAB=ESTDAB-074
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 8,12
ST   D3S1358: 16,17
ST   D5S818: 10,11
ST   D7S820: 10
ST   FGA: 19,22
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 15,18
DI   NCIt; C3510; Cutaneous melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_6793 ! WM1791C
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 02-05-24; Version: 23
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RX   PubMed=2253310; DOI=10.1007/BF00046337;
RA   Herlyn M.;
RT   "Human melanoma: development and progression.";
RL   Cancer Metastasis Rev. 9:101-112(1990).
//
RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
//
RX   PubMed=17260012; DOI=10.1038/sj.onc.1210252;
RA   Jonsson G., Dahl C., Staaf J., Sandberg T., Bendahl P.-O., Ringner M.,
RA   Guldberg P., Borg A.;
RT   "Genomic profiling of malignant melanoma using tiling-resolution
RT   arrayCGH.";
RL   Oncogene 26:4738-4748(2007).
//
RX   PubMed=19340423; DOI=10.1007/s00262-009-0701-z;
RA   Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T.,
RA   Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.;
RT   "HLA and melanoma: multiple alterations in HLA class I and II
RT   expression in human melanoma cell lines from ESTDAB cell bank.";
RL   Cancer Immunol. Immunother. 58:1507-1515(2009).
//
RX   PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006;
RA   Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L.,
RA   Borg A., Pawelec G., Guldberg P.;
RT   "Mutual exclusivity analysis of genetic and epigenetic drivers in
RT   melanoma identifies a link between p14 ARF and RARbeta signaling.";
RL   Mol. Cancer Res. 11:1166-1178(2013).
//