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Cellosaurus HS181 (CVCL_C229)

[Text version]
Cell line name HS181
Synonyms KIe001-A
Accession CVCL_C229
Resource Identification Initiative To cite this cell line use: HS181 (RRID:CVCL_C229)
Comments From: Karolinska Institutet; Stockholm; Sweden.
Registration: Swiss research registry; BAG-hES-IMP-0009.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-09.
Omics: SNP array analysis.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A8HR (HS181 EGFP-2A-SCL)CVCL_A8HS (HS181 EGFP-2A-RUNX1c)CVCL_EG08 (HS181-GFP)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=12832363; DOI=10.1093/humrep/deg290
Hovatta O., Mikkola M., Gertow K., Stromberg A.-M., Inzunza J., Hreinsson J., Rozell B., Blennow E., Andang M., Ahrlund-Richter L.
A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells.
Hum. Reprod. 18:1404-1409(2003)

PubMed=17572666; DOI=10.1038/nbt1318
Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W., Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B., Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M., Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A., Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S., Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P., Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K., King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D., Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M., Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N., O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y., Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F., Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J., Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H., Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T., Tuuri T., van den Brink S., Vintersten K., Vuoristo S., Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18930318; DOI=10.1016/j.leukres.2008.08.028
Catalina P., Bueno C., Montes R., Nieto Ruiz de Zarate A.I., Ligero G., Sanchez L., Jara-Acevedo M., Rasillo A., Orfao A., Cigudosa J.C., Hovatta O., Greaves M.F., Menendez P.
Genetic stability of human embryonic stem cells: a first-step toward the development of potential hESC-based systems for modeling childhood leukemia.
Leuk. Res. 33:980-990(2009)

PubMed=20198446; DOI=10.1007/s11626-010-9308-0; PMCID=PMC2855803
Strom S., Holm F., Bergstrom R., Stromberg A.-M., Hovatta O.
Derivation of 30 human embryonic stem cell lines -- improving the quality.
In Vitro Cell. Dev. Biol. Anim. 46:337-344(2010)

PubMed=20641038; DOI=10.1002/stem.471; PMCID=PMC2996086
Gutierrez-Aranda I., Ramos-Mejia V., Bueno C., Munoz-Lopez M., Real P.J., Macia A., Sanchez L., Ligero G., Garcia-Parez J.L., Menendez P.
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection.
Stem Cells 28:1568-1570(2010)

PubMed=20736931; DOI=10.1038/mt.2010.179; PMCID=PMC2997587
Ramos-Mejia V., Melen Frajlich G.J., Sanchez L., Gutierrez-Aranda I., Ligero G., Cortes J.L., Real P.J., Bueno C., Menendez P.
Nodal/activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage.
Mol. Ther. 18:2173-2181(2010)

PubMed=21217828; DOI=10.1371/journal.pone.0015329; PMCID=PMC3013107
Strom S., Rodriguez-Wallberg K., Holm F., Bergstrom R., Eklund L., Stromberg A.-M., Hovatta O.
No relationship between embryo morphology and successful derivation of human embryonic stem cell lines.
PLoS ONE 5:E15329-E15329(2010)

PubMed=24463987; DOI=10.1038/ncomms4195
Rodin S., Antonsson L., Niaudet C., Simonson O.E., Salmela E., Hansson E.M., Domogatskaya A., Xiao Z.-J., Damdimopoulou P., Sheikhi M., Inzunza J., Nilsson A.-S., Baker D.E.C., Kuiper R., Sun Y., Blennow E., Nordenskjold M., Grinnemo K.-H., Kere J., Betsholtz C., Hovatta O., Tryggvason K.
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment.
Nat. Commun. 5:3195.1-3195.13(2014)

PubMed=32339905; DOI=10.1016/j.scr.2020.101810
Main H., Hedenskog M., Acharya G., Hovatta O., Lanner F.
Karolinska Institutet Human Embryonic Stem Cell Bank.
Stem Cell Res. 45:101810-101810(2020)

Cross-references
Cell line databases/resources hPSCreg; KIe001-A
SKIP; SKIP001792
Encyclopedic resources Wikidata; Q54896297
Gene expression databases GEO; GSM569193
GEO; GSM569194
GEO; GSM1293456
GEO; GSM1293457
GEO; GSM1293458
GEO; GSM1293459
Entry history
Entry creation06-Jun-2012
Last entry update10-Sep-2024
Version number16