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Cellosaurus BIONi010-C-64 (CVCL_C1NT)

[Text version]
Cell line name BIONi010-C-64
Synonyms BIONi010-C-CYP3A4-2TA-Nluc; BIONi010-C-T2A-Nanoluciferase reporter cl. 29
Accession CVCL_C1NT
Resource Identification Initiative To cite this cell line use: BIONi010-C-64 (RRID:CVCL_C1NT)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: African.
Characteristics: Using CRISPR/Cas9 a T2A-Nluc construct was inserted at the C-terminus of one of the alleles of CYP3A4 (PubMed=35598806).
Genetic integration: Method=CRISPR/Cas9; Gene=NanoLuc (Note=19 kDa ATP-independent bright luminescent protein derived from O.gracilirostris).
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1E68 (BIONi010-C)
Sex of cell Male
Age at sampling 18Y
Category Induced pluripotent stem cell
Publications

PubMed=35598806; DOI=10.1016/j.reprotox.2022.05.005
Altmaier S., Meiser I., Lemesre E., Chanrion B., Steeg R., Leonte L.E., Holst B., Nielsen B.S., Clausen C., Schmidt K., Vinggaard A.M., Zimmermann H., Neubauer J.C., Rasmussen M.A.
Human iPSC-derived hepatocytes in 2D and 3D suspension culture for cryopreservation and in vitro toxicity studies.
Reprod. Toxicol. 111:68-80(2022)

Cross-references
Cell line databases/resources hPSCreg; BIONi010-C-64
Biological sample resources BioSamples; SAMEA10534760
Encyclopedic resources Wikidata; Q114310751
Entry history
Entry creation22-Sep-2022
Last entry update10-Sep-2024
Version number5