Cellosaurus cell line KATO III Ola-R (CVCL

Cross-references
Cell line name	KATO III Ola-R
Synonyms	KATO-III/olaparib-resistant; Olaparib-resistant KATO-III
Accession	CVCL_C1ND
Resource Identification Initiative	To cite this cell line use: KATO III Ola-R (RRID:CVCL_C1ND)
Comments	Population: Japanese. Selected for resistance to: ChEBI; CHEBI_83766; Olaparib. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
Disease	Down syndrome (NCIt: C2993) Gastric signet ring cell adenocarcinoma (NCIt: C5250) Down syndrome (ORDO: Orphanet_870)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0371 (KATO III)
Sex of cell	Male
Age at sampling	57Y
Category	Cancer cell line
Publications	PubMed=32028591; DOI=10.3390/cancers12020334; PMCID=PMC7072281 Kim J.W., Min A., Im S.-A., Jang H., Kim Y.J., Kim H.-J., Lee K.-H., Kim T.-Y., Lee K.W., Oh D.-Y., Kim J.-H., Bang Y.-J. TDP1 and TOP1 modulation in olaparib-resistant cancer determines the efficacy of subsequent chemotherapy. Cancers (Basel) 12:334.1-334.17(2020)
Encyclopedic resources	Wikidata; Q114311804
Entry history
Entry creation	22-Sep-2022
Last entry update	19-Dec-2024
Version number	5