Cellosaurus cell line HSJD-DIPG-014b (CVCL

Cross-references
Cell line name	HSJD-DIPG-014b
Synonyms	Hospital Sant Joan de Deu-Diffuse Intrinsic Pontine Glioma-008
Accession	CVCL_C1N3
Resource Identification Initiative	To cite this cell line use: HSJD-DIPG-014b (RRID:CVCL_C1N3)
Comments	Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
Sequence variations	Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (PubMed=31439867). Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Leu484Phefs*5 (c.1451dup); ClinVar=VCV000871469; Zygosity=Unspecified (PubMed=31439867).
Disease	Diffuse intrinsic pontine glioma (NCIt: C94764) Diffuse intrinsic pontine glioma (ORDO: Orphanet_497188)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=31439867; DOI=10.1038/s41467-019-11732-6; PMCID=PMC6706443 Fons N.R., Sundaram R.K., Breuer G.A., Peng S., McLean R.L., Kalathil A.N., Schmidt M.S., Carvalho D.M., Mackay A., Jones C., Carcaboso A.M., Nazarian J., Berens M.E., Brenner C., Bindra R.S. PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma. Nat. Commun. 10:3790.1-3790.10(2019)
Cell line databases/resources	cancercelllines; CVCL_C1N3
Encyclopedic resources	Wikidata; Q114311666
Entry history
Entry creation	22-Sep-2022
Last entry update	19-Dec-2024
Version number	6