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Cellosaurus TT10902 (CVCL_C1MP)

[Text version]
Cell line name TT10902
Accession CVCL_C1MP
Resource Identification Initiative To cite this cell line use: TT10902 (RRID:CVCL_C1MP)
Comments Population: Chinese.
Doubling time: 54.9 +- 0.1 hours (PubMed=29100338).
Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (PubMed=29100338).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=29100338).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=29100338).
Disease Diffuse intrinsic pontine glioma (NCIt: C94764)
Diffuse intrinsic pontine glioma (ORDO: Orphanet_497188)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=29100338; DOI=10.18632/oncotarget.19656; PMCID=PMC5652732
Xu C., Liu X.-Q., Geng Y.-B., Bai Q.-R., Pan C.-C., Sun Y., Chen X., Yu H., Wu Y.-L., Zhang P., Wu W.-H., Wang Y., Wu Z., Zhang J.-T., Wang Z.-H., Yang R., Lewis J., Bigner D.D., Zhao F.-P., He Y.-P., Yan H., Shen Q., Zhang L.-W.
Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors.
Oncotarget 8:76644-76655(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C1MP
Encyclopedic resources Wikidata; Q114313134
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number6