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Cellosaurus HB-2 (CVCL_C1LF)

[Text version]
Cell line name HB-2
Synonyms HB-second generation
Accession CVCL_C1LF
Resource Identification Initiative To cite this cell line use: HB-2 (RRID:CVCL_C1LF)
Comments Characteristics: Increased tumorigenicity compared to the parent cell line. Established from a tumor obtained from inoculation of the parent cell line in nude mice (PubMed=20464641).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Transformant: ChEBI; CHEBI_29865; Benzo[a]pyrene.
Derived from site: In situ; Oral cavity, oral mucosa; UBERON=UBERON_0003729.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6E44 (HIOEC-B(a)P-96)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=20464641; DOI=10.1007/s12032-010-9558-4
Ye D.-X., Zhou X.-J., Pan H.-Y., Jiang Q., Zhong L.-P., Chen W.-T., Zhang Z.-Y.
Establishment and characterization of an HPV16 E6/E7-expressing oral squamous cell carcinoma cell line with enhanced tumorigenicity.
Med. Oncol. 28:1331-1337(2011)

Cross-references
Encyclopedic resources Wikidata; Q114311564
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7