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Cellosaurus KB319 (CVCL_C1K3)

[Text version]
Cell line name KB319
Accession CVCL_C1K3
Resource Identification Initiative To cite this cell line use: KB319 (RRID:CVCL_C1K3)
Comments Population: African American.
Characteristics: The transfected plasmid pMSTKneo DNA was integrated at the telomere of chromosome 13 (PubMed=7957062; PubMed=8423817).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pLR309).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C1HU (LM217)
Children:
CVCL_C1K4 (KB319 subclone E)
Sex of cell Male
Age at sampling <1M
Category Transformed cell line
Publications

PubMed=1972815; DOI=10.1007/BF01233356
Murnane J.P.
Influence of cellular sequences on instability of plasmid integration sites in human cells.
Somat. Cell Mol. Genet. 16:195-209(1990)

PubMed=8423817; DOI=10.1128/mcb.13.2.977-983.1993; PMCID=PMC358982
Murnane J.P., Yu L.-C.
Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome break.
Mol. Cell. Biol. 13:977-983(1993)

PubMed=7957062; DOI=10.1002/j.1460-2075.1994.tb06822.x; PMCID=PMC395436
Murnane J.P., Sabatier L., Marder B.A., Morgan W.F.
Telomere dynamics in an immortal human cell line.
EMBO J. 13:4953-4962(1994)

Cross-references
Encyclopedic resources Wikidata; Q114311805
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7