ID   betaG I/17
AC   CVCL_C1JU
SY   betaG 1/17; BG I/17
DR   Wikidata; Q114310746
RX   PubMed=9166666;
RX   PubMed=9166667;
CC   Characteristics: Transfected with a pCB6-INS-Neo construct. Expresses 10 times more insulin than the parent cell line (PubMed=9166666).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6081; INS.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCIt; C17262; X-Ray.
CC   Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
CC   Cell type: Pancreatic beta cell; CL=CL_0000169.
CC   Breed/subspecies: NEDH; RS=RS:0000603.
DI   NCIt; C121566; Rat insulinoma
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
HI   CVCL_U435 ! RIN 1046-38
SX   Male
AG   666D
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=9166666; DOI=10.2337/diab.46.6.958;
RA   Clark S.A., Quaade C., Constandy H., Hansen P., Halban P.A., Ferber S.,
RA   Newgard C.B., Normington K.;
RT   "Novel insulinoma cell lines produced by iterative engineering of
RT   GLUT2, glucokinase, and human insulin expression.";
RL   Diabetes 46:958-967(1997).
//
RX   PubMed=9166667; DOI=10.2337/diab.46.6.968;
RA   Hohmeier H.-E., BeltrandelRio H., Clark S.A., Henkel-Rieger R.,
RA   Normington K., Newgard C.B.;
RT   "Regulation of insulin secretion from novel engineered insulinoma cell
RT   lines.";
RL   Diabetes 46:968-977(1997).
//